Description

n-Methyl-n-[(2-Propen-1-Yloxy)Carbonyl]-L-Alanine CAS NO 918531-01-8 is a specialized, high-purity amino acid derivative designed for advanced chemical synthesis. This compound is valued for its role as a key chiral building block and protecting group intermediate in the development of complex molecules. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of peptides and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a specialized amino acid derivative for constructing complex peptide sequences in solid-phase and solution-phase peptide chemistry.
• Protecting Group Chemistry: Serves as an intermediate where the allyloxycarbonyl (Alloc) group is employed for temporary amine protection in multi-step organic syntheses.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Utilized in academic and industrial R&D for probing enzyme mechanisms and studying protein-protein interactions.
• Process Development: Employed in scaling up synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	n-Methyl-n-[(2-Propen-1-Yloxy)Carbonyl]-L-Alanine
CAS No.	918531-01-8
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	N-Methyl-N-[(allyloxy)carbonyl]-L-alanine; L-Alanine, N-methyl-N-[(2-propen-1-yloxy)carbonyl]-; N-Alloc-N-methyl-L-alanine; (S)-2-(Methyl((2-propen-1-yloxy)carbonyl)amino)propanoic acid; N-Methyl-N-(allyloxycarbonyl)alanine; Alloc-N-methyl-L-alanine; N-Alloc-N-Me-L-Ala-OH; Allyl methylcarbamoyl-L-alaninate
EINECS	Contact for details

Quality Control

Our n-Methyl-n-[(2-Propen-1-Yloxy)Carbonyl]-L-Alanine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.