Description

(S)-3-p-Tolylpent-4-Enamide CAS NO 918149-66-3 is a high-purity chiral amide compound featuring a tolyl group and an unsaturated pentenamide backbone. This specific stereochemistry makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure active ingredients for advanced crop protection products.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the study and development of new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & R&D Laboratories: A valuable tool for synthetic organic chemistry research in universities and corporate R&D centers.
• Material Science Precursor: Potential intermediate for the synthesis of specialized polymers or organic electronic materials.

Basic Information

Product Name	(S)-3-p-Tolylpent-4-Enamide
CAS No.	918149-66-3
Molecular Formula	C₁₄H₁₉NO
Molecular Weight	217.31 g/mol
Synonyms	(S)-3-(4-Methylphenyl)pent-4-enamide; (3S)-3-(4-Methylphenyl)-4-pentenamide; (S)-3-(p-Tolyl)-4-pentenamide; (S)-3-(4-Methylphenyl)pent-4-enoic acid amide; (S)-3-p-Tolyl-4-pentenamide; (S)-3-(4-Tolyl)pent-4-enamide; 918149-66-3; (S)-3-(4-Methylphenyl)pent-4-en-1-amide
EINECS	Contact for details

Quality Control

Our (S)-3-p-Tolylpent-4-Enamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets stringent specifications for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.