Description

3,5-Difluoro-4-(Hydroxymethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in its dual functionality, serving as a key building block in cross-coupling reactions while offering a handle for further derivatization via its hydroxymethyl group. This compound is critically needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring fluorinated aromatic components.
• Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymers, resins, and organic electronic materials.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Diagnostic Reagents: Potential use in the development of fluorescent probes and sensors due to the presence of fluorine atoms.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the study of biological processes via boronic acid-diol interactions.

Basic Information

Product Name	3,5-Difluoro-4-(Hydroxymethyl)Phenylboronic Acid
CAS No.	917969-79-0
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	(3,5-Difluoro-4-(hydroxymethyl)phenyl)boronic acid; 4-(Hydroxymethyl)-3,5-difluorobenzeneboronic acid; 3,5-Difluoro-4-(hydroxymethyl)benzeneboronic acid; B-[3,5-Difluoro-4-(hydroxymethyl)phenyl]boronic acid; 917969-79-0; (4-(Hydroxymethyl)-3,5-difluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(Hydroxymethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.