Description

3-Chloro-5-Hydroxybenzamide is a versatile halogenated aromatic amide building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily sought after by research and development chemists, process engineers, and manufacturers in the fine chemical and life science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators, leveraging its halogen and hydroxyl functional groups.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Dye & Pigment Intermediate: Functions as a precursor in the synthesis of complex azo dyes and high-performance pigments.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research within universities and CROs.

Basic Information

Product Name	3-Chloro-5-Hydroxybenzamide
CAS No.	917388-33-1
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	5-Amino-3-chlorophenol; 3-Chloro-5-hydroxybenzoic acid amide; 3-Chloro-5-hydroxybenzamide; 3-Chloro-5-hydroxybenzanilide; 3-Chloro-5-hydroxybenzamide; 3-Chloro-5-hydroxybenzamide; 3-Chloro-5-hydroxybenzamide; 3-Chloro-5-hydroxybenzamide
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-Hydroxybenzamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.