Description

(R)-(+)-7,7′-Bis[Di(3,5-Dimethylphenyl)Phosphino]-2,2′,3,3′-Tetrahydro-1,1′-Spirobiindene CAS NO 917377-75-4 is a high-performance, chiral bisphosphine ligand essential for asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, critical for producing single-isomer intermediates in pharmaceutical and fine chemical synthesis. This product is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking efficient routes to chiral molecules.

Application

• As a privileged ligand for asymmetric hydrogenation of olefins, ketones, and imines.
• Catalyst component in enantioselective C-C bond-forming reactions, such as cross-couplings and allylic substitutions.
• Key chiral inducer in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Development of novel catalytic systems for academic and industrial research in organic synthesis.
• Production of agrochemicals and flavors & fragrances requiring high optical purity.
• Use in process chemistry for scaling up enantioselective catalytic reactions.

Basic Information

Product Name	(R)-(+)-7,7′-Bis[Di(3,5-Dimethylphenyl)Phosphino]-2,2′,3,3′-Tetrahydro-1,1′-Spirobiindene
CAS No.	917377-75-4
Molecular Formula	C58H56P2
Molecular Weight	815.00 g/mol
Synonyms	(R)-DTBM-SEGPHOS; (R)-3,3′,5,5′-Tetra-tert-butyl-5,5′-di(3,5-dimethylphenyl)-[4,4′-bi-1,3-benzodioxole]-6,6′-diylbis(diphenylphosphine); (R)-DTBM-SEGPHOS Ligand; (R)-5,5′-Bis[di(3,5-dimethylphenyl)phosphino]-4,4′-bi-1,3-benzodioxole; (R)-DTBM-SEGPHOS (CAS 917377-75-4); (R)-7,7′-Bis(di(3,5-dimethylphenyl)phosphino)-2,2′,3,3′-tetrahydro-1,1′-spirobiindene; (R)-DTBM-SEGPhos; SEGPHOS derivative, (R)-DTBM-
EINECS	Contact for details

Quality Control

Our (R)-DTBM-SEGPHOS is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive catalytic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and identity. Our quality system supports compliance with cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool environment. This compound is strictly light-sensitive (protect from all light exposure) and easily oxidized (store under inert atmosphere). Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.