Description

(R)-(+)-7,7'-Bis(Diphenylphosphino)-2,2',3,3'-Tetrahydro-1,1'-Spirobiindane, Min. 97% (R)-Sdp is a high-purity, chiral bisphosphine ligand essential for asymmetric catalysis. Its rigid spirobiindane backbone provides exceptional stereocontrol, making it a critical component for producing enantiomerically pure intermediates in pharmaceutical and fine chemical synthesis. This ligand is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for advanced catalytic transformations.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key catalyst in the production of active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee).
• Cross-Coupling Reactions: Used in asymmetric versions of Suzuki-Miyaura, Heck, and other C-C bond-forming reactions.
• Agrochemical Manufacturing: Enables the synthesis of chiral herbicides, fungicides, and pesticides with high biological activity.
• Academic & Industrial R&D: A valuable tool for developing novel catalytic methodologies and exploring new reaction pathways in process chemistry.
• Fine Chemical Production: For the manufacture of high-value chiral flavors, fragrances, and electronic chemicals.

Basic Information

Product Name	(R)-(+)-7,7'-Bis(Diphenylphosphino)-2,2',3,3'-Tetrahydro-1,1'-Spirobiindane, Min. 97% (R)-Sdp
CAS No.	917377-74-3
Molecular Formula	C41H34P2
Molecular Weight	588.66 g/mol
Synonyms	(R)-(+)-SDP; (R)-SDP Ligand; (R)-7,7'-Bis(diphenylphosphino)-2,2',3,3'-tetrahydro-1,1'-spirobiindane; (R)-2,2',3,3'-Tetrahydro-7,7'-bis(diphenylphosphino)-1,1'-spirobiindane; (R)-Spirobiindanebis(diphenylphosphine); (R)-Spiro-SDP; (R)-SDPPhos; (R)-H8-BINAP (structural analog)
EINECS	Contact for details

Quality Control

Every batch of our (R)-SDP ligand is manufactured and tested under strict quality management systems to ensure consistent, high-performance material. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, enantiomeric excess, and key impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical applications, ensuring reliable supply and traceability for critical process development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The product is easily oxidized and moisture-sensitive; handling should be performed in a controlled, dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Enantiomeric Excess (HPLC)	Min. 99.0% ee
Loss on Drying	Max. 0.5%
Residue on Ignition	Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.