Description

3-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Propionic Acid Methyl Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial advanced pharmaceutical intermediate and building block in modern organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create biaryl structures, a common motif in many functional molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Can be employed in the development of molecular probes and bioconjugation tools.
• Academic & Industrial R&D: A versatile reagent for methodology development and complex molecule synthesis in laboratory settings.

Basic Information

Product Name	3-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Propionic Acid Methyl Ester
CAS No.	917024-58-9
Molecular Formula	C16H23BO4
Molecular Weight	290.16 g/mol
Synonyms	Methyl 3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate; 3-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propionic acid methyl ester; 3-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoic acid methyl ester; 3-(3-(Pinacolatoboryl)phenyl)propionic Acid Methyl Ester; Methyl 3-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propionate; Boric acid, B-[3-(2-methoxy-2-oxoethyl)phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 3-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Propionic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.