Description

2'-Fluoro-(2-Bromophenyl)Acetic Acid is a high-purity fluorinated and brominated aromatic acetic acid derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both fluorine and bromine substituents, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the halogenated phenylacetic acid scaffold.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a probe or linker molecule in bioconjugation and the development of chemical tools for studying biological systems.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling rapid diversification of molecular structures.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories worldwide.

Basic Information

Product Name	2'-Fluoro-(2-Bromophenyl)Acetic Acid
CAS No.	916792-43-3
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	(2-Bromo-2-fluorophenyl)acetic acid; 2-Bromo-2-fluorobenzeneacetic acid; α-(2-Bromo-2-fluorophenyl)acetic acid; 2-(2-Bromo-2-fluorophenyl)acetic acid; 2-Bromo-2-fluorophenylacetic acid; (2-Bromophenyl)(fluoro)acetic acid; 916792-43-3; 2'-Fluoro-2-bromophenylacetic acid
EINECS	Contact for details

Quality Control

Every batch of 2'-Fluoro-(2-Bromophenyl)Acetic Acid is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, NMR (1H, 13C, 19F), and mass spectrometry for structural confirmation and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.