Description

2-Bromo-4-Fluoro-6-Methylbenzonitrile is a high-purity, multi-functional halogenated aromatic nitrile building block. This compound is valued for its unique substitution pattern, which makes it a versatile intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the halogen atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology Probes: Employed in the design of molecular probes and tags due to the reactivity of the nitrile and halogen functional groups.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling rapid diversification.
• Organic Electronic Materials: Investigated as a building block for electron-transport materials in OLEDs and other electronic devices.

Basic Information

Product Name	2-Bromo-4-Fluoro-6-Methylbenzonitrile
CAS No.	916792-09-1
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	2-Bromo-4-fluoro-6-methylbenzonitrile; Benzonitrile, 2-bromo-4-fluoro-6-methyl-; 4-Fluoro-2-bromo-6-methylbenzonitrile; 6-Methyl-2-bromo-4-fluorobenzonitrile; 2-Bromo-4-fluoro-6-methyl-benzonitrile; 916792-09-1 (CAS); 2-Br-4-F-6-Me-BnCN
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Fluoro-6-Methylbenzonitrile is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.