Description

4-Methoxy-2-(Trifluoromethyl)Benzamide is a high-purity, specialized benzamide derivative distinguished by its methoxy and trifluoromethyl substituents, which confer unique electronic and steric properties. This compound is a critical pharmaceutical intermediate and research chemical, valued for its role in the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by R&D laboratories, custom synthesis providers, and manufacturers in the pharmaceutical and agrochemical sectors seeking to develop novel compounds with enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a precursor for developing new-generation herbicides and pesticides, leveraging the trifluoromethyl group for improved lipophilicity and biological activity.
• Material Science: Used in the research and development of advanced organic materials, including liquid crystals and polymers, where its specific substituents can modulate material properties.
• Chemical Synthesis: Employed in custom and contract synthesis as a versatile reagent for introducing the 4-methoxy-2-(trifluoromethyl)benzoyl moiety into more complex molecular architectures.
• Life Science Research: Acts as a reference standard, biochemical tool, or inhibitor in various biochemical and pharmacological research studies.

Basic Information

Product Name	4-Methoxy-2-(Trifluoromethyl)Benzamide
CAS No.	916420-82-1
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2-(Trifluoromethyl)-4-methoxybenzamide; 4-Methoxy-2-(trifluoromethyl)benzoic acid amide; 4-Methoxy-α,α,α-trifluoro-o-toluamide; Benzamide, 4-methoxy-2-(trifluoromethyl)-; 916420-82-1; 4-Methoxy-2-trifluoromethylbenzamide; 2-Trifluoromethyl-4-methoxybenzamide
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(Trifluoromethyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical R&D and synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Handle and store in accordance with good laboratory and chemical hygiene practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.