Description

3-[2-Fluoro-4-(Trifluoromethyl)Phenyl]Propionic Acid is a high-purity fluorinated aromatic propionic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and binding affinity in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated motifs for improved drug-like properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronics: Employed in the creation of specialized monomers and polymers for organic light-emitting diodes (OLEDs) and semiconductor materials.
• Chemical Research & Development: A versatile reagent for constructing complex fluorinated aromatic compounds in academic and industrial R&D settings.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific fluorinated phenylpropionic acid architectures.

Basic Information

Product Name	3-[2-Fluoro-4-(Trifluoromethyl)Phenyl]Propionic Acid
CAS No.	916420-38-7
Molecular Formula	C10H6F4O2
Molecular Weight	234.15 g/mol
Synonyms	2-Fluoro-4-(trifluoromethyl)benzenepropanoic Acid; 3-(2-Fluoro-4-trifluoromethylphenyl)propionic Acid; 2-Fluoro-α-methyl-4-(trifluoromethyl)benzenepropanoic Acid; 3-(2-Fluoro-4-(trifluoromethyl)phenyl)propanoic Acid; α-Methyl-2-fluoro-4-trifluoromethylbenzenepropanoic Acid; 916420-38-7; FTFP Propionic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-[2-Fluoro-4-(Trifluoromethyl)Phenyl]Propionic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for regulatory submissions and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.