Description

4-Bromo-3-Hydroxybenzonitrile is a versatile brominated aromatic nitrile derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a hydroxyl group ortho to a nitrile, makes it a valuable building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and insecticides, where the bromine atom offers a site for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers due to its aromatic and polar functional groups.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and enzyme activity.

Basic Information

Product Name	4-Bromo-3-Hydroxybenzonitrile
CAS No.	916213-60-0
Molecular Formula	C7H4BrNO
Molecular Weight	198.02 g/mol
Synonyms	3-Hydroxy-4-bromobenzonitrile; 4-Bromo-3-hydroxybenzenecarbonitrile; 2-Bromo-5-cyanophenol; 5-Cyano-2-bromophenol; Benzonitrile, 4-bromo-3-hydroxy-; 916213-60-0; 4-Bromo-3-hydroxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Hydroxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.