Description

8-(Cyclopropylmethyl)-1,4-Dioxaspiro[4.5]Decane-8-Carbonitrile is a high-purity, specialized organic intermediate featuring a unique spirocyclic acetal-protected nitrile structure. This compound matters as a critical building block in advanced organic synthesis, offering a protected carbonyl equivalent and a versatile nitrile functional group for further derivatization. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring spirocyclic or constrained ring systems.
• Agrochemical Synthesis: Used in research and development for creating novel pesticides and herbicides with specific activity profiles.
• Organic Chemistry Research: Serves as a versatile building block for constructing complex molecular architectures in academic and industrial R&D settings.
• Material Science Precursor: Potential use in the development of specialty polymers or functional materials requiring specific nitrile or protected ketone functionalities.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological testing.

Basic Information

Product Name	8-(Cyclopropylmethyl)-1,4-Dioxaspiro[4.5]Decane-8-Carbonitrile
CAS No.	916159-85-8
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	8-(Cyclopropylmethyl)-1,4-dioxaspiro[4.5]decane-8-carbonitrile; 1,4-Dioxaspiro[4.5]decane-8-carbonitrile, 8-(cyclopropylmethyl)-; 8-Cyclopropylmethyl-1,4-dioxaspiro[4.5]decane-8-carbonitrile; Cyclopropylmethyl Dioxaspirodecane Carbonitrile; Spirocyclic Acetal Nitrile Intermediate; 8-(Cyclopropylmethyl)-8-cyano-1,4-dioxaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our 8-(Cyclopropylmethyl)-1,4-Dioxaspiro[4.5]Decane-8-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.