Description

n-Boc-3,3-Diphenyl-L-Alanine Benzyl Ester is a sophisticated, high-purity protected amino acid derivative essential for advanced organic synthesis. This compound is a critical chiral building block, prized for its role in constructing complex peptide frameworks and pharmaceutical intermediates. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs, enzyme inhibitors, and other bioactive compounds.
• Peptide Chemistry: Used in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods for introducing the sterically hindered 3,3-diphenylalanine moiety.
• Protease Inhibitor Development: Serves as a core structure in the research and production of inhibitors targeting specific proteolytic enzymes.
• Chemical Biology & Probe Synthesis: Employed in the creation of labeled peptides and molecular probes for studying biological pathways and protein interactions.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and methodological research in synthetic organic chemistry.

Basic Information

Product Name	n-Boc-3,3-Diphenyl-L-Alanine Benzyl Ester
CAS No.	915750-93-5
Molecular Formula	C27H29NO4
Molecular Weight	431.52 g/mol
Synonyms	(2S)-3,3-Diphenyl-2-[(tert-butoxycarbonyl)amino]propanoic acid benzyl ester; Benzyl (2S)-3,3-diphenyl-2-[(tert-butoxycarbonyl)amino]propanoate; Boc-Diphenylalanine(OBzl)-OH; Boc-L-3,3-Diphenylalanine benzyl ester; N-tert-Butoxycarbonyl-3,3-diphenyl-L-alanine benzyl ester; N-Boc-3,3-Diphenyl-L-Ala-OBzl; (S)-Benzyl 2-((tert-butoxycarbonyl)amino)-3,3-diphenylpropanoate
EINECS	Contact for details

Quality Control

Our n-Boc-3,3-Diphenyl-L-Alanine Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.