Description

7-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indazole is a high-value, synthetically versatile boronic ester derivative of indazole, serving as a critical building block in modern organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used to construct novel heterocyclic scaffolds for the development of new herbicides, fungicides, and insecticides.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, through polymerization or functionalization.
• Chemical Biology: Serves as a probe or linker in bioconjugation chemistry and the development of biochemical tools.
• Academic & R&D: A fundamental reagent for methodological development in cross-coupling chemistry and heterocycle functionalization.
• Custom Synthesis: Provides a handle for the late-stage diversification of indazole-containing compounds in contract research and manufacturing.

Basic Information

Product Name	7-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indazole
CAS No.	915411-02-8
Molecular Formula	C₁₃H₁₇BN₂O₂
Molecular Weight	244.10 g/mol
Synonyms	1H-Indazole-7-boronic acid, pinacol ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 7-Indazolylboronic acid pinacol ester; 7-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 915411-02-8; Pinacol 7-indazoleboronate
EINECS	Contact for details

Quality Control

Every batch of 7-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indazole is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure batch-to-batch consistency and high purity. Our standard quality commitment includes rigorous testing via HPLC, NMR (¹H and ¹³C), and mass spectrometry. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.