Description

Elotuzumab is a humanized monoclonal antibody specifically designed to target the Signaling Lymphocytic Activation Molecule Family member 7 (SLAMF7) protein. This targeted mechanism of action makes it a critical therapeutic agent in modern oncology. It is primarily utilized in combination regimens for the treatment of specific hematologic malignancies. Elotuzumab CAS NO 915296-00-3 represents a significant advancement in immunotherapy, offering a targeted approach for improved patient outcomes.

Application

• Oncotherapeutic Agent: Primary use in the treatment of multiple myeloma, particularly in combination with other immunomodulatory drugs and dexamethasone.
• Immunotherapy Research: Serves as a key reagent in preclinical and clinical research focused on SLAMF7-mediated immune cell activation and cancer cell killing.
• Biopharmaceutical Manufacturing: Used as an active pharmaceutical ingredient (API) in the production of finished dosage forms for commercial distribution.
• Clinical Development: Employed in the formulation of investigational new drugs (INDs) for ongoing clinical trials exploring new indications or combination therapies.
• Reference Standard: Functions as a high-purity biological reference standard for quality control and assay development in analytical laboratories.

Basic Information

Item	Detail
Product Name	Elotuzumab
CAS No.	915296-00-3
Molecular Formula	Contact for details
Molecular Weight	Approx. 145 kDa
Synonyms	HuLuc63; Anti-SLAMF7 Monoclonal Antibody; BMS-901608; Immunoglobulin G1, anti-(human signaling lymphocytic activation molecule F7) (human-Mus musculus monoclonal HuLuc63 γ1-chain), disulfide with human-Mus musculus monoclonal HuLuc63 κ-chain, dimer; SLAMF7 Inhibitor
EINECS	Contact for details

Quality Control

Our Elotuzumab is manufactured and tested under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and safety, meeting the stringent requirements for biopharmaceutical active substances. A Certificate of Analysis (COA) documenting specifications such as purity by SEC-HPLC, host cell protein levels, endotoxin content, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear to slightly opalescent solution
Identification (HPLC/LC-MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Content (UV/A280)	As per COA
Potency (Cell-based Assay)	Within specified range
Endotoxin	< 1.0 EU/mg
Host Cell Protein	< 100 ppm
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.