Description

(S)-3-Cyanopiperidine Hydrochloride is a high-purity chiral building block essential for modern pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, especially for neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and scale-up production of new chemical entities (NCEs).
• Asymmetric Synthesis: Employed as a precursor for introducing the (S)-3-cyanopiperidine moiety into target molecules with high stereochemical purity.
• Medicinal Chemistry & Drug Discovery: A valuable scaffold for constructing compound libraries and exploring structure-activity relationships (SAR).
• Process Chemistry & Route Scouting: Used in the development of efficient and scalable synthetic pathways for commercial drug manufacturing.
• Biochemical Research: Potential use as a tool compound or ligand in enzyme inhibition studies.

Basic Information

Product Name	(S)-3-Cyanopiperidine Hydrochloride
CAS No.	915226-72-1
Molecular Formula	C6H11ClN2
Molecular Weight	146.62 g/mol
Synonyms	(S)-Piperidine-3-carbonitrile hydrochloride; (3S)-Piperidine-3-carbonitrile hydrochloride; (S)-3-Cyano-piperidine HCl; (S)-3-Piperidinecarbonitrile hydrochloride; (S)-3-Cyanopiperidine HCl; (S)-3-Piperidyl cyanide hydrochloride; (S)-3-Cyano piperidine hydrochloride salt
EINECS	Contact for details

Quality Control

Our (S)-3-Cyanopiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.