Description

1-Piperidinecarboxylic Acid, 3-(Aminocarbonyl)-, 1,1-Dimethylethyl Ester, (3R)- is a high-purity, chiral piperidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its role as a protected intermediate, enabling the precise construction of complex molecules with defined stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is required for biological activity.
• Peptidomimetics & Protease Inhibitors: Serves as a constrained scaffold for designing peptide mimics and enzyme inhibitors.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop novel chiral ligands for asymmetric synthesis.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new chemical entities.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 3-(Aminocarbonyl)-, 1,1-Dimethylethyl Ester, (3R)-
CAS No.	915226-43-6
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	(3R)-3-Carbamoyl-1-piperidinecarboxylic acid tert-butyl ester; tert-Butyl (3R)-3-carbamoylpiperidine-1-carboxylate; (R)-1-Boc-3-carbamoylpiperidine; (R)-3-Carbamoylpiperidine-1-carboxylic acid tert-butyl ester; (R)-1-N-Boc-3-piperidinecarboxamide; (R)-N-Boc-3-piperidinecarboxamide; (3R)-1-(tert-Butoxycarbonyl)piperidine-3-carboxamide; BOC-(R)-3-Piperidinecarboxamide
EINECS	Contact for details

Quality Control

Our production of 1-Piperidinecarboxylic Acid, 3-(Aminocarbonyl)-, 1,1-Dimethylethyl Ester, (3R)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our quality systems are designed to support cGMP and ISO standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.