Description

Benzeneacetic Acid, α,3-Difluoro- is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique difluoro-substituted structure makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for active ingredient development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a precursor in the development of fluorinated organic compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Advanced Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, aiming to alter surface properties, chemical resistance, and thermal stability.
• Custom Synthesis & Contract Manufacturing: An essential reagent for fine chemical and custom synthesis houses specializing in producing complex, fluorinated organic molecules for client-specific projects.

Basic Information

Product Name	Benzeneacetic Acid, α,3-Difluoro-
CAS No.	915030-45-4
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2-(3,4-Difluorophenyl)acetic Acid; (3,4-Difluorophenyl)acetic Acid; α,3-Difluorobenzeneacetic Acid; 3,4-Difluorobenzeneacetic Acid; 2-(3,4-Difluorophenyl)ethanoic Acid; NSC 405124; 915030-45-4
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetic Acid, α,3-Difluoro- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by validated methods (e.g., HPLC, GC, NMR) is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.