Description

(2R,4R)-4-(tert-Butyldimethylsilyloxy)-n-Methoxy-N,2-Dimethyloct-7-Enamide is a high-purity, stereochemically defined synthetic intermediate of significant importance in advanced pharmaceutical research and development. Its core value lies in its role as a key chiral building block for the synthesis of complex bioactive molecules, particularly in medicinal chemistry. This compound is essential for researchers and process chemists in the pharmaceutical and biotechnology industries who are developing novel therapeutic agents, especially those targeting metabolic and neurological pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic compounds.
• Process Development: Serves as a reference standard and starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with specific three-dimensional configurations.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and pharmacological assays.
• Academic & Institutional R&D: Employed in university and research institute laboratories for cutting-edge organic and bioorganic chemistry projects.

Basic Information

Product Name	(2R,4R)-4-(tert-Butyldimethylsilyloxy)-n-Methoxy-N,2-Dimethyloct-7-Enamide
CAS No.	914922-88-6
Molecular Formula	C₁₈H₃₇NO₃Si
Molecular Weight	343.58 g/mol
Synonyms	(2R,4R)-4-[(tert-Butyldimethylsilyl)oxy]-N-methoxy-N,2-dimethyloct-7-enamide; (2R,4R)-4-(TBDMSO)-N-methoxy-N,2-dimethyloct-7-enamide; 4-(tert-Butyldimethylsiloxy)-n-methoxy-N,2-dimethyl-(2R,4R)-oct-7-enamide; TBDMS-protected chiral enamide intermediate; (2R,4R)-4-(tert-Butyldimethylsilyloxy)-N-methoxy-N,2-dimethyl-7-octenamide
EINECS	Contact for details

Quality Control

Our (2R,4R)-4-(tert-Butyldimethylsilyloxy)-n-Methoxy-N,2-Dimethyloct-7-Enamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.