Description

2-Amino-5-Bromo-3-Chlorobenzonitrile is a high-purity, multi-functional halogenated benzonitrile derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which incorporates reactive amino, bromo, chloro, and nitrile functional groups, enabling precise and diverse chemical transformations. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules for active ingredient development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic core and multiple substitution sites.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes, tags, and linkers in bioconjugation and target identification studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Amino-5-Bromo-3-Chlorobenzonitrile
CAS No.	914636-86-5
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	5-Bromo-3-chloro-2-aminobenzonitrile; 3-Chloro-5-bromo-2-aminobenzonitrile; 2-Amino-5-bromo-3-chlorobenzene carbonitrile; 2-Cyano-4-bromo-6-chloroaniline; Benzonitrile, 2-amino-5-bromo-3-chloro-; (2-Amino-5-bromo-3-chlorophenyl) cyanide
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Bromo-3-Chlorobenzonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.