Description

2-Amino-3-Bromo-5-Chlorobenzonitrile is a high-purity, multi-functional halogenated benzonitrile derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic positioning of its amino, bromo, chloro, and nitrile functional groups, which enable precise and versatile chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to construct complex molecular architectures for active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its halogenated aromatic core contributes to biological activity and stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: An invaluable reagent for medicinal chemistry, process chemistry, and methodology development, enabling cross-coupling, nucleophilic substitution, and cyclization reactions.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex heterocyclic dyes and high-performance pigments due to its reactive sites.

Basic Information

Product Name	2-Amino-3-Bromo-5-Chlorobenzonitrile
CAS No.	914636-84-3
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	3-Bromo-5-chloro-2-aminobenzonitrile; 2-Amino-3-bromo-5-chlorobenzene carbonitrile; Benzonitrile, 2-amino-3-bromo-5-chloro-; 5-Chloro-3-bromoanthranilonitrile; 3-Bromo-5-chloroanthranilonitrile; 2-Cyano-6-bromo-4-chloroaniline
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Bromo-5-Chlorobenzonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical-grade material meets high-purity requirements for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.