Description

4-Chloro-3-Iodobenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it a valuable intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This high-purity compound is essential for medicinal chemists and R&D professionals engaged in developing new active ingredients, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in cross-coupling reactions like Suzuki and Sonogashira couplings.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its rigid, substituted benzene structure.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to diverse R&D needs.

Basic Information

Product Name	4-Chloro-3-Iodobenzonitrile
CAS No.	914106-26-6
Molecular Formula	C7H3ClIN
Molecular Weight	263.46 g/mol
Synonyms	3-Iodo-4-chlorobenzonitrile; 4-Chloro-3-iodo-benzonitrile; Benzonitrile, 4-chloro-3-iodo-; 4-Chloro-3-iodobenzene carbonitrile; 3-Iodo-4-chlorobenzene carbonitrile; 914106-26-6; 4-Chloro-3-iodobenzonitrile (CAS 914106-26-6)
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for 4-Chloro-3-Iodobenzonitrile to ensure batch-to-batch consistency and high purity, typically ≥97% (HPLC). Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. Our quality system is designed to meet the exacting standards of pharmaceutical and fine chemical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.