Description

4-Bromo-1-Fluoro-2-Naphthaleneboronic Acid is a high-purity, multi-functional boronic acid derivative serving as a critical building block in advanced organic synthesis. Its core value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients, functional polymers, and electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those with naphthalene-based scaffolds.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials.
• Cross-Coupling Reactions: Essential reagent for Suzuki-Miyaura coupling to form carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Chemical Biology & Proteomics: Potential use in developing molecular probes and inhibitors for studying biological pathways.
• Academic & Industrial R&D: Serves as a versatile starting material for method development and discovery chemistry in research laboratories.

Basic Information

Product Name	4-Bromo-1-Fluoro-2-Naphthaleneboronic Acid
CAS No.	913836-09-6
Molecular Formula	C₁₀H₇BBrFO₂
Molecular Weight	268.88 g/mol
Synonyms	(4-Bromo-1-fluoro-2-naphthyl)boronic acid; 2-Naphthaleneboronic acid, 4-bromo-1-fluoro-; 4-Bromo-1-fluoro-2-naphthaleneboronic acid pinacol ester (common derivative); 4-Br-1-F-2-NapB(OH)₂; B-(4-Bromo-1-fluoro-2-naphthyl)boronic acid; 913836-09-6; 4-Bromo-1-fluoro-2-boronaphthalene
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Fluoro-2-Naphthaleneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.