Description

2-Bromo-6-Fluorophenylboronic Acid is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex biaryl structures. The consistent quality and reliable supply of this reagent are critical for accelerating drug discovery and material science projects.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the specific halogen substitution pattern is required for bioactivity.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and as a scaffold for functional materials.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and CDMO companies offering bespoke synthesis services to the pharmaceutical industry.

Basic Information

Product Name	2-Bromo-6-Fluorophenylboronic Acid
CAS No.	913835-80-0
Molecular Formula	C6H5BBrFO2
Molecular Weight	218.82 g/mol
Synonyms	(2-Bromo-6-fluorophenyl)boronic acid; 2-Fluoro-6-bromobenzeneboronic acid; B-(2-Bromo-6-fluorophenyl)boronic acid; 2-Bromo-6-fluorobenzeneboronic acid; Boronic acid, B-(2-bromo-6-fluorophenyl)-; 913835-80-0; 2-Br-6-F-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.