Description

3-(4-Methoxy)Benzyloxy-5-(Trifluoromethyl)Benzeneboronic Acid 98 is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing trifluoromethyl and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the stability and bioactivity of the trifluoromethyl group.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and semiconductors.
• Suzuki-Miyaura Cross-Coupling: A fundamental reagent for forming carbon-carbon bonds between aryl halides and this boronic acid, a cornerstone reaction in medicinal chemistry.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and bioconjugation tools due to its boronic acid functionality.
• Ligand Synthesis: Acts as a starting material for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(4-Methoxy)Benzyloxy-5-(Trifluoromethyl)Benzeneboronic Acid 98
CAS No.	913835-77-5
Molecular Formula	C15H14BF3O4
Molecular Weight	326.08 g/mol
Synonyms	[3-(4-Methoxybenzyloxy)-5-(trifluoromethyl)phenyl]boronic acid; 3-[(4-Methoxybenzyl)oxy]-5-(trifluoromethyl)benzeneboronic acid; 3-(4-Methoxybenzyloxy)-5-trifluoromethylphenylboronic acid; 3-(p-Methoxybenzyloxy)-5-(trifluoromethyl)phenylboronic acid; 913835-77-5; Boronic acid, B-[3-[(4-methoxyphenyl)methoxy]-5-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 3-(4-Methoxy)Benzyloxy-5-(Trifluoromethyl)Benzeneboronic Acid 98 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure a typical purity of ≥98% and conformity to customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.