Description

3-(Carboxymethoxy)-5-Fluorobenzeneboronic Acid 96 is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a carboxylic acid moiety for further derivatization, enabling the construction of complex fluorinated aromatic structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly where the 5-fluorobenzeneboronic acid scaffold is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that incorporate fluorinated aromatic rings for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a monomer or building block for synthesizing novel fluorinated polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The boronic acid group facilitates palladium-catalyzed carbon-carbon bond formation, a cornerstone reaction for constructing biaryl systems in medicinal chemistry.
• Peptide & Conjugate Chemistry: The carboxylic acid functionality allows for amide bond formation, enabling the attachment of the fluorinated aromatic unit to peptides, proteins, or other biomolecules.
• Chemical Biology Probes: Utilized in the development of fluorinated probes and tags for imaging, diagnostics, and studying biological processes.

Basic Information

Product Name	3-(Carboxymethoxy)-5-Fluorobenzeneboronic Acid 96
CAS No.	913835-56-0
Molecular Formula	C8H8BFO5
Molecular Weight	213.96 g/mol
Synonyms	5-Fluoro-3-(carboxymethoxy)benzeneboronic Acid; (5-Fluoro-3-[(carboxy)methoxy]phenyl)boronic Acid; 3-Carboxymethoxy-5-fluorophenylboronic Acid; 3-Fluoro-5-boronobenzyloxyacetic Acid; 913835-56-0; B-(5-Fluoro-3-[(carboxymethoxy)]phenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 3-(Carboxymethoxy)-5-Fluorobenzeneboronic Acid 96 is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the specified 96% minimum purity and consistent performance in cross-coupling reactions. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.