Description

5-(Trifluoromethyl)Benzene-1,3-Diboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing trifluoromethyl groups for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Organic Electronic Materials: Serves as a building block for creating conjugated polymers and small molecules used in OLEDs, organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized to create boronic acid-based sensors and probes for detecting sugars, peroxides, and other analytes in research settings.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing aromatic and fluorinated segments into specialty polymers.

Basic Information

Product Name	5-(Trifluoromethyl)Benzene-1,3-Diboronic Acid
CAS No.	913835-35-5
Molecular Formula	C7H7BF6O4
Molecular Weight	271.75 g/mol
Synonyms	1,3-Phenylenebis(boronic acid), 5-(trifluoromethyl)-; 3,5-Bis(borono)benzotrifluoride; 5-(Trifluoromethyl)-1,3-benzenediboronic Acid; m-Trifluoromethylbenzene-1,3-diboronic Acid; [3,5-Bis(boronic acid)phenyl]trifluoromethane; 913835-35-5; 5-Trifluoromethylisophthalic Acid Diboronate
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Benzene-1,3-Diboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure a minimum purity of 98% and batch-to-batch consistency. Certificates of Analysis (COA) with full traceability are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.