Description

Ll-37 Gke is a synthetic peptide derivative, a key intermediate in advanced pharmaceutical research and development. This compound is crucial for its role in the synthesis of novel therapeutic agents, particularly in the fields of antimicrobial and immunomodulatory drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in peptide-based drug development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide-based drugs targeting infectious diseases and immune disorders.
• Antimicrobial Peptide Research: Used in the development and study of LL-37 peptide analogs to enhance stability, bioavailability, and therapeutic efficacy.
• Immunology Studies: Employed in research to understand and modulate innate immune responses and inflammation pathways.
• Bioconjugation: Acts as a substrate for developing peptide-drug conjugates (PDCs) and other targeted therapeutic modalities.
• Reference Standard: Functions as a high-purity analytical standard for quality control and method validation in peptide manufacturing.
• Preclinical Development: Utilized in formulation studies and pharmacokinetic/pharmacodynamic (PK/PD) modeling for candidate drug molecules.

Basic Information

Item	Details
Product Name	Ll-37 Gke
CAS No.	913736-92-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LL-37 GKE; LL37-GKE; Cathelicidin LL-37 derivative; Antimicrobial Peptide LL-37 analog; GKE-LL-37; Peptide LL-37 fragment; Synthetic LL-37 peptide; LL-37 (GKE)
EINECS	Contact for details

Quality Control

Our Ll-37 Gke is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) after opening and to allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.