Description

(11Br)-2,6-Bis(Diphenylphosphino)-N,n-Dimethyldinaphtho(2,1-D:1',2'-F)-1,3,2-Dioxaphosphepin-4-Amine, Kanata Purity is a high-purity, advanced chiral phosphine ligand designed for sophisticated catalytic transformations. Its value lies in its unique steric and electronic properties, which enable exceptional enantioselectivity and activity in asymmetric synthesis. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for creating high-value chiral intermediates and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, critical for producing single-enantiomer pharmaceutical compounds.
• Cross-Coupling Catalysis: Employed in palladium- or nickel-catalyzed reactions such as Suzuki-Miyaura, Negishi, or Buchwald-Hartwig couplings to form C-C and C-N bonds with high efficiency.
• Asymmetric Allylic Substitution: Facilitates the creation of chiral centers via Tsuji-Trost and related reactions for complex molecule construction.
• Pharmaceutical Intermediate Synthesis: Used in the research and scale-up production of chiral active pharmaceutical ingredients (APIs) and advanced intermediates.
• Academic & Industrial R&D: Serves as a valuable tool for developing new catalytic methodologies and exploring novel reaction pathways in process chemistry.
• Agrochemical Synthesis: Applied in the development of enantiomerically pure pesticides and herbicides.

Basic Information

Item	Details
Product Name	(11Br)-2,6-Bis(Diphenylphosphino)-N,n-Dimethyldinaphtho(2,1-D:1',2'-F)-1,3,2-Dioxaphosphepin-4-Amine, Kanata Purity
CAS No.	913617-04-6
Molecular Formula	C45H36BrNO2P2
Molecular Weight	788.61 g/mol
Synonyms	Kanata Catalyst Ligand; (11Br)-BINAP-Derived Phosphine Ligand; Br-DM-DIOP Analogue; Chiral Dioxaphosphepin Ligand; Asymmetric Hydrogenation Ligand; (R)- or (S)-2,6-Bis(diphenylphosphino)-N,N-dimethyl-4-amino-dinaphthodioxaphosphepin Bromo Derivative; 913617-04-6
EINECS	Contact for details

Quality Control

Our Kanata Purity grade is produced under strict quality management systems to ensure batch-to-batch consistency for critical research and development. Each lot undergoes comprehensive analysis, including HPLC for purity and chiral integrity, NMR for structural confirmation, and elemental analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific impurities is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. The compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.