Description

1H-Indole-1-Carboxylic Acid, 2-Borono-5-[[[2-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Ethyl]Amino]Methyl]-, 1-(1,1-Dimethylethyl) Ester is a sophisticated, multi-functional organic compound featuring indole, boronic acid, and silyl-protected hydroxyl groups. This molecule is of significant value as a key synthetic intermediate or building block in advanced organic and medicinal chemistry. It is primarily required by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of complex target molecules, including potential drug candidates and chemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting complex biological pathways.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors, leveraging its boronic acid functionality which can act as a transition-state analog.
• Bioconjugation & Probe Synthesis: Employed in creating chemical probes for activity-based protein profiling (ABPP) or diagnostic agents due to its reactive handles.
• Peptidomimetic Chemistry: Acts as a scaffold for designing peptidomimetics, where the indole core mimics aromatic amino acid side chains.
• Material Science Research: Potential use in synthesizing functionalized organic materials or ligands for catalysis, given its protected reactive sites.
• Academic & Contract Research: Essential for exploratory synthetic chemistry in academic institutions and contract research organizations (CROs).

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 2-Borono-5-[[[2-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Ethyl]Amino]Methyl]-, 1-(1,1-Dimethylethyl) Ester
CAS No.	913388-73-5
Molecular Formula	C23H39BN2O4Si
Molecular Weight	446.46 g/mol
Synonyms	tert-Butyl 2-borono-5-((2-((tert-butyldimethylsilyl)oxy)ethylamino)methyl)-1H-indole-1-carboxylate; 1-(tert-Butyl) 2-borono-5-((2-((tert-butyldimethylsilyl)oxy)ethylamino)methyl)-1H-indole-1-carboxylate; BOC-Indole-Boronic Acid TBS Ester Derivative; 913388-73-5; (1-(tert-Butoxycarbonyl)-5-(((2-((tert-butyldimethylsilyl)oxy)ethyl)amino)methyl)-1H-indol-2-yl)boronic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing batch-specific results from NMR, HPLC, and mass spectrometry are available upon request. We adhere to a cGMP-compliant quality management system for traceability and reproducibility, essential for critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (argon or nitrogen) after each use to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.