Description

tert-Butyl Formylcarbamate is a specialized carbamate derivative serving as a versatile building block in advanced organic synthesis. Its primary value lies in its role as a protected formylglycine equivalent, enabling the controlled introduction of formyl groups into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of protease inhibitors, enzyme modulators, and other bioactive molecules requiring formylglycine motifs.
• Peptide Chemistry: Used in the preparation of modified peptides and peptidomimetics, where it acts as a protected aldehyde functionality for subsequent conjugation or cyclization reactions.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced properties.
• Material Science Research: Employed in the development of specialty polymers and functional materials that incorporate carbamate or formyl groups.
• Chemical Biology Probes: Useful for labeling studies and the synthesis of molecular probes targeting aldehyde-processing enzymes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and process development.

Basic Information

Product Name	tert-Butyl Formylcarbamate
CAS No.	913344-40-8
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	N-(tert-Butoxycarbonyl)formamide; Formic acid N-(tert-butoxycarbonyl)amide; BOC-Formamide; (tert-Butoxy)(formylamino)methanone; N-Formyl-N-Boc-amine; tert-Butyl N-formylcarbamate; N-Boc-formamide; 2-Methyl-2-propanyl formylcarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl Formylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.