Description

3-(Trifluoromethoxy)Anisole is a high-value fluorinated aromatic building block characterized by its trifluoromethoxy and methoxy substituents. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex fluorinated aromatic systems.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new reaction pathways and material properties.

Basic Information

Product Name	3-(Trifluoromethoxy)Anisole
CAS No.	912820-26-9
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	1-Methoxy-3-(trifluoromethoxy)benzene; 3-(Trifluoromethoxy)phenyl methyl ether; m-(Trifluoromethoxy)anisole; 3-Methoxy-1-(trifluoromethoxy)benzene; Benzene, 1-methoxy-3-(trifluoromethoxy)-; 3-Trifluoromethoxyanisole
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)Anisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including GC, HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.