Description

n-Carbamoylglutamic Acid Diethyl Ester is a high-purity, protected glutamic acid derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a versatile, reactive scaffold for constructing complex molecules, particularly in the development of pharmaceuticals and bioactive compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for peptide mimetics and other nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Peptidomimetic Research: Used to create modified peptide structures with enhanced stability or biological activity for therapeutic applications.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, or plant growth regulators.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, dyes, and complex organic molecules requiring a protected glutamic acid moiety.
• Bioconjugation Chemistry: Useful in linker chemistry for attaching payloads to antibodies, proteins, or other biomolecules in ADC (Antibody-Drug Conjugate) development.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	n-Carbamoylglutamic Acid Diethyl Ester
CAS No.	911658-62-3
Molecular Formula	C10H18N2O5
Molecular Weight	246.26 g/mol
Synonyms	Diethyl N-Carbamoyl-L-glutamate; L-Glutamic acid, N-carbamoyl-, diethyl ester; Diethyl (2S)-2-(carbamoylamino)pentanedioate; (S)-Diethyl 2-(carbamoylamino)pentanedioate; NCG-DEE; Carbamoylglutamic Acid Diethyl Ester; Glutamic Acid Derivative Diethyl Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-Carbamoylglutamic Acid Diethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.