Description

5-Chloro-2,4-Difluorobenzeneboronic Acid, 97% is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing a difluorophenyl or chlorodifluorophenyl moiety.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a boronic acid coupling partner to form carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl systems.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in both academic and industrial R&D laboratories.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis.

Basic Information

Product Name	5-Chloro-2,4-Difluorobenzeneboronic Acid, 97%
CAS No.	911645-24-4
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	(5-Chloro-2,4-difluorophenyl)boronic acid; 5-Chloro-2,4-difluorobenzeneboronic acid; 2,4-Difluoro-5-chlorophenylboronic acid; Boronic acid, B-(5-chloro-2,4-difluorophenyl)-; 911645-24-4; 5-Chloro-2,4-difluorophenyl-B(OH)2; Benzeneboronic acid, 5-chloro-2,4-difluoro-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,4-Difluorobenzeneboronic Acid, 97% is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing specifications and test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.