Description

Phosphine, [(1S,3S)-1,3-Dimethyl-1,3-Propanediyl]Bis[Bis[4-(1,1-Dimethylethyl)Phenyl]- (9Ci) is a specialized organophosphorus compound featuring a chiral, sterically hindered phosphine ligand structure. This compound matters for its role as a highly selective ligand in asymmetric catalysis, enabling the synthesis of chiral molecules with high enantiomeric purity. It is primarily needed by R&D chemists and process engineers in the pharmaceutical and fine chemical industries for developing advanced synthetic routes.

Application

• Asymmetric Hydrogenation: As a chiral ligand for the catalytic hydrogenation of prochiral olefins, ketones, and imines to produce enantiomerically pure intermediates.
• Pharmaceutical Intermediate Synthesis: For the production of active pharmaceutical ingredients (APIs) requiring high stereochemical control.
• Cross-Coupling Catalysis: Potential use as a ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for C-C bond formation.
• Academic & Industrial Research: A valuable tool for methodology development in organic synthesis and catalysis research.
• Fine Chemical Manufacturing: Enabling the synthesis of complex, high-value specialty chemicals, including flavors, fragrances, and agrochemicals.
• Catalyst Screening Libraries: As a component in high-throughput screening for discovering new catalytic systems.

Basic Information

Product Name	Phosphine, [(1S,3S)-1,3-Dimethyl-1,3-Propanediyl]Bis[Bis[4-(1,1-Dimethylethyl)Phenyl]- (9Ci)
CAS No.	911415-22-0
Molecular Formula	C41H56P2
Molecular Weight	610.83 g/mol
Synonyms	(1S,3S)-2,4-Bis[bis(4-tert-butylphenyl)phosphino]pentane; (S,S)-2,4-Bis[bis(4-tert-butylphenyl)phosphino]pentane; (S,S)-Pentane-2,4-diylbis[bis(4-tert-butylphenyl)phosphine]; (S,S)-BisP* Pentane; Chiral Diphosphine Ligand; DTBP-PentanePhos; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of this high-value chiral ligand is produced and controlled under strict quality management to ensure identity, purity, and enantiomeric excess. Our quality protocols include advanced chromatographic and spectroscopic methods to verify critical parameters. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (ee), and full analytical data is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.