Description

(R)-4-(1-Aminoethyl)Benzonitrile Hydrochloride is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs), particularly in neurological and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where specific stereochemistry is crucial for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of other high-value specialty chemicals requiring the (R)-1-phenylethylamine structural motif.
• Academic and R&D: Utilized in research laboratories for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	(R)-4-(1-Aminoethyl)Benzonitrile Hydrochloride
CAS No.	911372-78-6
Molecular Formula	C9H10N2•HCl
Molecular Weight	182.65 g/mol (Free base: 146.19 g/mol)
Synonyms	(R)-4-(1-Aminoethyl)benzonitrile HCl; (R)-α-Methyl-4-cyanobenzylamine Hydrochloride; (R)-1-(4-Cyanophenyl)ethylamine Hydrochloride; (R)-4-Cyanophenethylamine Hydrochloride; (R)-p-Cyanophenethylamine HCl; (R)-4-(Aminoethyl)benzonitrile Hydrochloride; (R)-1-(4-Cyanophenyl)ethanamine Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-4-(1-Aminoethyl)Benzonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.