Description

Ammonium Glycyrrhizinate Trihydrate is the ammonium salt of glycyrrhizic acid, a key bioactive triterpenoid saponin derived from licorice root. This compound is highly valued for its potent sweetening properties, which are significantly stronger than sucrose, and its well-documented anti-inflammatory and skin-soothing effects. It serves as a critical functional ingredient for manufacturers in the cosmetics, personal care, pharmaceutical, and food & beverage industries, where natural, multifunctional actives are in high demand.

Application

• Cosmetics & Skincare: Used as a soothing and anti-irritant agent in creams, lotions, serums, and after-sun products to calm sensitive or inflamed skin.
• Pharmaceuticals: Employed in formulations for its anti-inflammatory and hepatoprotective properties, often found in throat lozenges, cough syrups, and topical anti-itch preparations.
• Oral Care: Incorporated into toothpastes and mouthwashes for its flavor-enhancing and mild anti-plaque benefits.
• Food & Beverage: Functions as a high-intensity natural sweetener and flavor modifier in confectionery, beverages, and dietary supplements.
• Nutraceuticals: Served as a key component in dietary supplements targeting digestive health, respiratory support, and adrenal function.
• Tobacco Industry: Utilized as a flavoring and moistening agent in certain tobacco products.

Basic Information

Product Name	Ammonium Glycyrrhizinate Trihydrate
CAS No.	911217-00-0
Molecular Formula	C42H65NO16 • 3H2O
Molecular Weight	839.97 g/mol (Anhydrous basis: 785.97)
Synonyms	Ammoniated Glycyrrhizin; Glycyrrhizic Acid Ammonium Salt Trihydrate; Glycyrrhizin Ammonium; 18β-Glycyrrhetinic Acid 3-O-(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranosiduronic Acid) Ammonium Salt Trihydrate; Magnasweet; Enoxolone O-β-D-Glucopyranosyl-(1→2)-O-β-D-glucopyranosiduronic Acid Ammonium Salt Trihydrate
EINECS	Contact for details

Quality Control

Our Ammonium Glycyrrhizinate Trihydrate is produced and tested under a strict quality management system. Each batch is analyzed to ensure it meets specifications for identity, purity, and potency, with testing typically including HPLC for assay, heavy metals, residual solvents, and microbiological limits. Certificates of Analysis (COA) documenting full compliance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 8.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Microbiological Total Plate Count	≤ 1000 cfu/g
Yeast & Mold	≤ 100 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.