Description

D(+)-Trehalose Dihydrate is a naturally occurring, non-reducing disaccharide sugar composed of two glucose molecules. This unique chemical structure provides exceptional stability, making it a highly effective protectant for proteins, enzymes, and cells against dehydration, heat, and freezing. It is a critical ingredient for industries requiring reliable stabilization and preservation, particularly in pharmaceuticals, biotechnology, and high-value food products. Its excellent solubility and mild sweetness further enhance its utility across diverse formulations.

Application

• Pharmaceutical Excipient & Stabilizer: Used as a cryoprotectant and lyoprotectant in the formulation of vaccines, monoclonal antibodies, and other biologic drugs to maintain efficacy during freeze-drying and storage.
• Biotechnology Reagent: Protects enzymes, antibodies, and labile proteins from denaturation and aggregation in diagnostic kits and research applications.
• Food & Nutraceutical Ingredient: Functions as a shelf-life extender, texture modifier, and sweetener in processed foods, health supplements, and sports nutrition products.
• Cosmetics & Personal Care: Acts as a natural humectant and moisturizer in skincare formulations to help maintain skin hydration.
• Cell Culture & Preservation: Employed in media formulations and as a protective agent for the long-term storage of mammalian cells, bacteria, and other sensitive biological materials.
• Agricultural & Seed Treatment: Used to enhance the stress tolerance and shelf life of seeds and beneficial microbial inoculants.

Basic Information

Product Name	D(+)-Trehalose Dihydrate
CAS No.	6138-23-4
Molecular Formula	C₁₂H₂₂O₁₁·2H₂O
Molecular Weight	378.33 g/mol
Synonyms	α,α-Trehalose Dihydrate; α-D-Glucopyranosyl-α-D-glucopyranoside Dihydrate; Mycose; Tremalose; Natural Trehalose; D-Trehalose Dihydrate; Trehalose BP/USP/EP; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol Dihydrate
EINECS	202-739-6

Quality Control

Our D(+)-Trehalose Dihydrate is manufactured under strict quality management systems. It is available in various grades, including high-purity Pharmaceutical (USP/EP/JP) and Food Grade (FCC), ensuring compliance with global regulatory requirements. Every batch undergoes rigorous analytical testing, including assay, optical rotation, and impurity profiling. A comprehensive Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed after each use to prevent absorption of atmospheric moisture, which can lead to caking and potential microbial growth.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Specific Optical Rotation	+197° to +201°
Water (Karl Fischer)	9.0% - 10.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Microbial Limits	Meets USP/EP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.