Description

(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-Amino-3-(4-Hydroxyphenyl)Propanoyl]Amino]Acetyl]Amino]Acetyl]Amino]-3-Phenylpropanoyl]Amino]-4-Methylpentanoic Acid is a high-purity, synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate for the synthesis of complex peptide-based therapeutics and diagnostic agents. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality intermediates for drug discovery, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel peptide-based drugs targeting metabolic, oncological, and neurological disorders.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for constructing specific amino acid sequences with defined stereochemistry.
• Research & Development: Critical reagent in academic and industrial R&D for studying peptide structure-activity relationships (SAR) and developing new therapeutic candidates.
• API Manufacturing: Intermediate in the multi-step production of complex peptide Active Pharmaceutical Ingredients (APIs) under GMP conditions.
• Bioconjugation: Potential use in creating peptide-drug conjugates or labeled peptides for diagnostic and targeted therapy applications.
• Biochemical Research: Tool compound for enzymatic studies, receptor binding assays, and proteomics research.

Basic Information

Item	Details
Product Name	(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-Amino-3-(4-Hydroxyphenyl)Propanoyl]Amino]Acetyl]Amino]Acetyl]Amino]-3-Phenylpropanoyl]Amino]-4-Methylpentanoic Acid
CAS No.	14-18-6
Molecular Formula	C30H39N7O8
Molecular Weight	625.67 g/mol
Synonyms	H-Tyr-Gly-Gly-Phe-Leu-OH; YGGFL; Leu-enkephalin, Tyr-Gly-Gly-Phe-Leu; (2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid; L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucine; Opioid peptide [Tyr5, Leu5] enkephalin; Enkephalin, Leu-; LE
EINECS	Contact for details

Quality Control

Our (2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-Amino-3-(4-Hydroxyphenyl)Propanoyl]Amino]Acetyl]Amino]Acetyl]Amino]-3-Phenylpropanoyl]Amino]-4-Methylpentanoic Acid is produced and tested under a stringent quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS and NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific pharmacopeial (e.g., USP) or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.