Description

3,3,3-Trifluoropropyl Methansulfonate is a specialized organofluorine building block and methanesulfonate ester. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the introduction of a trifluoropropyl group is required. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those incorporating fluorine to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoropropyl moiety can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving characteristics like chemical resistance, surface energy, and thermal stability.
• Cross-coupling Reactions: Acts as an alkylating agent in palladium-catalyzed and other cross-coupling methodologies to form carbon-carbon bonds.
• Fluorinated Surfactant & Coating Precursor: Used in the synthesis of specialty surfactants and coatings that require oil- and water-repellent properties.

Basic Information

Product Name	3,3,3-Trifluoropropyl Methansulfonate
CAS No.	911116-16-0
Molecular Formula	C5H9F3O3S
Molecular Weight	206.18 g/mol
Synonyms	3,3,3-Trifluoropropyl Methanesulfonate; Methanesulfonic Acid 3,3,3-Trifluoropropyl Ester; 3,3,3-Trifluoropropan-1-yl Methanesulfonate; 3,3,3-Trifluoropropyl Mesylate; 1-Trifluoropropyl Methanesulfonate; 3,3,3-Trifluoropropyl Methanesulphonate; 3,3,3-Trifluoroprop-1-yl Methanesulfonate
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoropropyl Methansulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP standards where applicable, ensuring reliability for pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.