Description

3-(4-Trifluoromethylsulfanyl-Phenyl)-Propionic Acid Ethyl Ester is a high-value fluorinated organic intermediate with a unique trifluoromethylthio (-SCF₃) functional group, prized for its ability to modulate the lipophilicity and metabolic stability of target molecules. This compound is essential for research and development chemists seeking to incorporate the highly sought-after SCF₃ moiety into advanced chemical architectures. It is primarily utilized in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, serving as a critical building block for innovators in life sciences and specialty chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the SCF₃ group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and tailored reactivity.
• Chemical Biology & Proteomics: Employed as a probe or labeling reagent in biochemical research due to the distinctive spectroscopic signature of the fluorine atoms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	3-(4-Trifluoromethylsulfanyl-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	910654-45-4
Molecular Formula	C₁₂H₁₁F₃O₂S
Molecular Weight	276.27 g/mol
Synonyms	Ethyl 3-[4-(Trifluoromethylthio)phenyl]propanoate; 3-[4-(Trifluoromethylsulfanyl)phenyl]propionic Acid Ethyl Ester; Ethyl 3-(4-((Trifluoromethyl)thio)phenyl)propionate; 4-(Trifluoromethylthio)benzenepropanoic Acid Ethyl Ester; 910654-45-4; SCHEMBL23545479; ZINC000095049676; AKOS040759246
EINECS	Contact for details

Quality Control

Our production of 3-(4-Trifluoromethylsulfanyl-Phenyl)-Propionic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.