Description

Boronic Acid, (6-Bromo-2-Fluoro-3-Pyridinyl)- is a high-purity, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and agrochemical development. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for coupling with various aryl/heteroaryl halides to create complex biaryl systems.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where its specific halogen and fluorine substitution pattern is valuable.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and tools for studying biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	Boronic Acid, (6-Bromo-2-Fluoro-3-Pyridinyl)-
CAS No.	910649-58-0
Molecular Formula	C6H4BBrFNO2
Molecular Weight	219.82 g/mol
Synonyms	(6-Bromo-2-fluoropyridin-3-yl)boronic acid; 6-Bromo-2-fluoro-3-pyridineboronic acid; 2-Fluoro-6-bromo-3-pyridinylboronic acid; (6-Bromo-2-fluoro-3-pyridinyl)boronic acid; 3-Borono-6-bromo-2-fluoropyridine; B-(6-Bromo-2-fluoro-3-pyridinyl)boronic acid; Boronic acid, B-(6-bromo-2-fluoro-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our Boronic Acid, (6-Bromo-2-Fluoro-3-Pyridinyl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and elemental analysis, to meet the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.