Description

Potassium [2-(Morpholin-4-yl)ethoxy]methyltrifluoroborate is a specialized organotrifluoroborate salt, a highly valuable class of reagents in modern synthetic chemistry. Its primary value lies in its exceptional stability and utility as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. This compound is particularly sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of C-C bonds, crucial for building biaryl and heteroaryl structures in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), especially those containing morpholine or ethylene glycol motifs.
• Agrochemical Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require complex, functionalized aromatic cores.
• Materials Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands or metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or probes for studying biological pathways and protein interactions.

Basic Information

Item	Detail
Product Name	Potassium [2-(Morpholin-4-yl)ethoxy]methyltrifluoroborate
CAS No.	910251-18-2
Molecular Formula	C8H15BF3KNO2
Molecular Weight	270.12 g/mol
Synonyms	Potassium (2-Morpholinoethoxy)methyltrifluoroborate; Potassium [(2-Morpholin-4-ylethoxy)methyl]trifluoroborate; Potassium Trifluoro[(2-morpholin-4-ylethoxy)methyl]borate; 2-Morpholinoethoxymethyltrifluoroborate Potassium Salt; (2-Morpholinoethoxy)methyltrifluoroborate Potassium Salt; K[Morph-CH2CH2O-CH2-BF3]; Potassium (Morpholinoethoxymethyl)trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium [2-(Morpholin-4-yl)ethoxy]methyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 11B, 19F) for structural confirmation and HPLC for purity assessment, to ensure it meets the high standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere (argon or nitrogen) after each use to prevent moisture absorption and degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0 %
NMR Purity (19F)	≥ 95%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.