Description

Potassium 1-Methyl-4-Trifluoroboratomethylpiperazine is a high-value organoboron reagent, specifically a potassium trifluoroborate salt, prized for its enhanced stability and handling properties compared to boronic acids. This compound serves as a critical building block in modern synthetic chemistry, enabling efficient cross-coupling reactions to construct complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in creating complex molecules for crop protection agents, herbicides, and fungicides.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and novel polymers.
• Chemical Biology & Probe Development: Facilitates the labeling and modification of biomolecules for diagnostic and research tools.
• Process Chemistry & Scale-up: Provides a stable, crystalline alternative to boronic acids for robust and scalable manufacturing processes.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploring new chemical space in organic synthesis.

Basic Information

Product Name	Potassium 1-Methyl-4-Trifluoroboratomethylpiperazine
CAS No.	1015484-22-6
Molecular Formula	C7H13BF3KN2
Molecular Weight	232.10 g/mol
Synonyms	Potassium (1-Methylpiperazin-4-yl)methyltrifluoroborate; 1-Methyl-4-(trifluoroboratomethyl)piperazine Potassium Salt; 4-(Trifluoroboratomethyl)-1-methylpiperazine Potassium Salt; Potassium Trifluoro(1-methylpiperazin-4-ylmethyl)borate; (1-Methyl-4-piperazinylmethyl)trifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 1-Methyl-4-Trifluoroboratomethylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) and store the container in a desiccator. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0 %
NMR Purity (¹H NMR)	≥ 95%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.