Description

Potassium 3-Trifluoroboratopropionate Ethyl Ester is a high-value organotrifluoroborate reagent, a stable and versatile building block for advanced organic synthesis. Its significance lies in its role as a key intermediate in cross-coupling reactions, particularly Suzuki-Miyaura couplings, enabling the efficient introduction of functionalized propionate groups into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators requiring specific propionate-based side chains.
• Materials Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a bioconjugation reagent or for the synthesis of molecular probes and labeled compounds.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing novel ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Product Name	Potassium 3-Trifluoroboratopropionate Ethyl Ester
CAS No.	1023357-64-3
Molecular Formula	C5H9BF3KO2
Molecular Weight	208.03 g/mol
Synonyms	Potassium (3-Ethoxy-3-oxopropyl)trifluoroboranuide; Ethyl 3-(Trifluoroboranyl)propanoate Potassium Salt; 3-(Ethoxycarbonyl)propyltrifluoroborate Potassium Salt; Potassium 3-(Ethoxycarbonyl)propyltrifluoroborate; Potassium 3-Carbethoxypropyltrifluoroborate; Potassium Trifluoro(3-ethoxy-3-oxopropyl)borate; Propanoic acid, 3-(trifluoroboranyl)-, ethyl ester, potassium salt (1:1)
EINECS	Contact for details

Quality Control

Our Potassium 3-Trifluoroboratopropionate Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by NMR/HPLC), boron and potassium content, and moisture levels. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (NMR / HPLC)	≥ 95%
Boron Content	4.8 - 5.4 %
Potassium Content	18.0 - 20.0 %
Water Content (KF)	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.