Description

Potassium Trifluoro(5-Formylpyridin-3-Yl)Borate is a high-purity organoboron reagent, specifically a potassium trifluoroborate salt, featuring a formylpyridine functional group. This compound is valued for its enhanced stability in air and moisture compared to traditional boronic acids, while remaining a highly effective coupling partner in key synthetic transformations. It is an essential building block for researchers and manufacturers in pharmaceutical development and advanced material science, enabling the synthesis of complex heterocyclic targets.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heteroaryl motifs present in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents that require specific pyridine-based architectures.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and conductive polymers, where the formyl group allows for further functionalization.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes, leveraging its bio-orthogonal reactivity.
• Scale-up Process Chemistry: Its improved handling properties make it suitable for transition from laboratory-scale discovery to pilot and commercial-scale manufacturing processes.

Basic Information

Product Name	Potassium Trifluoro(5-Formylpyridin-3-Yl)Borate
CAS No.	1245906-60-8
Molecular Formula	C6H4BF3KNO
Molecular Weight	209.01 g/mol
Synonyms	Potassium (5-Formylpyridin-3-yl)trifluoroborate; 3-Formyl-5-pyridyltrifluoroborate Potassium Salt; 5-Formyl-3-pyridyltrifluoroboronic Acid Potassium Salt; Potassium 3-Formyl-5-pyridyltrifluoroborate; (5-Formyl-3-pyridinyl)trifluoroborate Potassium; Potassium Trifluoro(3-formyl-5-pyridyl)borate; Potassium (3-Formyl-5-pyridinyl)trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(5-Formylpyridin-3-Yl)Borate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B) for structural confirmation and HPLC for purity assessment, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture uptake, which can affect reactivity and stability. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to ensure optimal shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹⁹F NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.