Description

Potassium [2,2-Difluoro-1-(Methoxy)Ethenyl]Trifluoroborate is a versatile and highly reactive organotrifluoroborate salt, a crucial class of reagents in modern synthetic chemistry. Its primary value lies in its exceptional stability and handling properties compared to traditional boronic acids, enabling more robust and efficient cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds, particularly for introducing difluorovinyl and methoxy-substituted vinyl groups into complex molecular architectures.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), especially those containing fluorine atoms for enhanced metabolic stability and bioavailability.
• Agrochemical Development: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the unique properties of the fluorine atom.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where specific fluorinated vinyl units are required.
• Peptide Modification and Bioconjugation: Useful for site-specific labeling and functionalization of biomolecules under mild conditions.
• Catalyst and Ligand Development: Acts as a precursor for novel catalytic systems and specialized ligands in transition metal catalysis.

Basic Information

Product Name	Potassium [2,2-Difluoro-1-(Methoxy)Ethenyl]Trifluoroborate
CAS No.	1131736-79-2
Molecular Formula	C3H3BF5KO
Molecular Weight	199.96 g/mol
Synonyms	Potassium (2,2-Difluoro-1-methoxyvinyl)trifluoroborate; Potassium (2,2-Difluoro-1-methoxyethenyl)trifluoroboranuide; (2,2-Difluoro-1-methoxyvinyl)trifluoroborate Potassium Salt; Potassium (Z)-2,2-Difluoro-1-methoxyvinyltrifluoroborate; Difluoro(methoxyvinyl)trifluoroborate Potassium Salt; K-DFMVTB; Potassium Trifluoro(2,2-difluoro-1-methoxyvinyl)borate
EINECS	Contact for details

Quality Control

Our Potassium [2,2-Difluoro-1-(Methoxy)Ethenyl]Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 97%
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.