Description

Potassium 1H-Pyrazole-4-Trifluoroborate is a versatile organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds containing pyrazole motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the incorporation of the pyrazole ring system.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: A stable, air- and moisture-tolerant organoboron reagent for forming carbon-carbon bonds between aryl/heteroaryl groups under mild conditions.
• Chemical Library Development: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening in drug discovery.
• Ligand Synthesis: Used to prepare sophisticated polydentate ligands for transition metal catalysis.

Basic Information

Product Name	Potassium 1H-Pyrazole-4-Trifluoroborate
CAS No.	1111732-81-0
Molecular Formula	C3H3BF3KN2
Molecular Weight	173.97 g/mol
Synonyms	Potassium (1H-Pyrazol-4-yl)trifluoroborate; Potassium Pyrazole-4-Trifluoroborate; 4-(Trifluoroborato)-1H-pyrazole, Potassium Salt; 1H-Pyrazole-4-trifluoroborate Potassium Salt; Potassium 4-Trifluoroborato-1H-pyrazole; Potassium 4-(Trifluoroboranyl)-1H-pyrazol-1-ide; Potassium 1H-Pyrazol-4-yltrifluoroborate; 4-Pyrazoleboronic Acid, Trifluoro-, Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 1H-Pyrazole-4-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F), HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Elemental Analysis	Within theoretical range

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.