Description

Potassium I-Propyltrifluoroborate is an organoboron reagent of significant importance in modern synthetic chemistry. Its primary value lies in its role as a stable, air-tolerant precursor for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require efficient and reliable building blocks for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling: A key reagent for coupling with aryl or vinyl halides to introduce the isopropyl group, enabling the synthesis of complex biaryl and styrene derivatives.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for creating analogs with branched alkyl motifs.
• Agrochemical Compound Development: Employed in constructing novel pesticide and herbicide molecules where the isopropyltrifluoroborate moiety is a critical structural component.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands or organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Applied in the creation of organic electronic materials, such as polymers or small molecules for OLEDs, where precise structural control is required.
• Chemical Biology Probes: Utilized in the synthesis of isotopically labeled or tagged compounds for metabolic pathway studies and bio-conjugation.

Basic Information

Product Name	Potassium I-Propyltrifluoroborate
CAS No.	1041642-13-0
Molecular Formula	C3H7BF3K
Molecular Weight	153.99 g/mol
Synonyms	Potassium Isopropyltrifluoroborate; Potassium (Propan-2-yl)trifluoroborate; Isopropyltrifluoroboronic Acid Potassium Salt; Potassium Isopropyl-BF3; Potassium Trifluoro(isopropyl)borate; 2-Propytrifluoroborate Potassium Salt; KIPr-BF3
EINECS	Contact for details

Quality Control

Our Potassium I-Propyltrifluoroborate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹¹B, ¹³C) and HPLC analysis, to ensure high chemical purity and consistent performance in coupling reactions. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability and batch-to-batch reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) and in a desiccator for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹¹B NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.